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ONCC-CBCN
ONCC Certified Breast Care Nurse
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Question: 1
Which of the following is a characteristic of triple-negative breast cancer?
1. Expression of estrogen receptor (ER)
2. Expression of progesterone receptor (PR)
3. Lack of expression of ER, PR, and HER2
wer: C
anation: Triple-negative breast cancer refers to a subtype of breast ca oes not express the estrogen receptor (ER), progesterone receptor (P an epidermal growth factor receptor 2 (HER2). This subtype accounts oximately 10-20% of all breast cancer cases and is often associated wi aggressive disease course and limited treatment options.
stion: 2
ch of the following breast cancer subtypes is characterized by the expression of the human epidermal growth factor receptor 2 (HER2)?
uminal A uminal B asal-like
ER2-enriched
Expression of human epidermal growth factor receptor 2 (HER2) Ans
Expl ncer
that d R), or
hum for
appr th a
more
Que
Whi over
1. L
2. L
3. B
4. H
Answer: D
Explanation: The HER2-enriched subtype of breast cancer is characterized by the overexpression of the human epidermal growth factor receptor 2 (HER2). It represents approximately 15-20% of all breast cancer cases and is associated with a more aggressive disease course. Targeted therapies, such as trastuzumab
(Herceptin), can effectively treat HER2-positive breast cancer.
Question: 3
Which of the following is a common long-term complication of radiation therapy in breast cancer patients?
eripheral neuropathy ulmonary fibrosis ephrotoxicity
wer: A
anation: Lymphedema is a common long-term complication of radiati py in breast cancer patients. It refers to the swelling of the arm or che ide of the treated breast due to damage to the lymphatic system. phedema can cause discomfort and impair arm function.
stion: 4
ch of the following is an established risk factor for the development of breast cancer?
igh dietary intake of fruits and vegetables
Lymphedema
P
P
N
Ans
Expl on
thera st on
the s Lym
Que
Whi
1. H
2. Regular physical exercise
3. Breastfeeding
4. Early menopause Answer: D
Explanation: Early menopause, defined as menopause occurring before the age
of 45, is an established risk factor for the development of breast cancer. It is associated with a longer lifetime exposure to estrogen, which can increase the risk of breast cancer.
Question: 5
agnetic resonance imaging (MRI) ltrasound
ammography
ositron emission tomography (PET)
wer: C
anation: Mammography is the gold standard imaging modality for bre er screening in the general population. It is effective in detecting early breast cancer and has been shown to reduce breast cancer-related ality.
stion: 6
ch hormone therapy medication is commonly used in the treatment of mone receptor-positive breast cancer?
Which imaging modality is considered the gold standard for breast cancer screening in the general population?
1. M
2. U
3. M
4. P
Ans
Expl ast
canc -
stage mort
Que
Whi hor
1. Trastuzumab
2. Tamoxifen
3. Bevacizumab
4. Pertuzumab
Explanation: Tamoxifen is a commonly used hormone therapy medication in the treatment of hormone receptor-positive breast cancer. It acts by blocking the estrogen receptors in breast cancer cells, suppressing their growth and reducing the risk of cancer recurrence.
ch of the following is a common side effect of chemotherapy in breast er patients?
eight gain air loss ypertension one loss
wer: B
anation: Hair loss, also known as alopecia, is a common side effect of motherapy in breast cancer patients. Chemotherapy drugs target rapidly ing cells, which include hair follicles, leading to hair loss. It is usuall
orary, and hair often regrows after treatment is completed.
stion: 8
Question: 7
Whi canc
1. W
2. H
3. H
4. B
Ans Expl
che
divid y
temp
Que
Which of the following genetic mutations is most commonly associated with hereditary breast and ovarian cancer syndrome?
1. TP53
2. BRCA2
3. BRCA1
Answer: C
loping breast and ovarian cancer compared to the general population.
stion: 9
ch of the following lymph nodes is typically the first to receive draina the breast?
nternal mammary lymph node xillary lymph node upraclavicular lymph node entinel lymph node
wer: D
anation: The sentinel lymph node is typically the first lymph node to ve drainage from the breast. It is the first lymph node along the lymp way from the primary tumor site and is often the target of sentinel ly biopsy to assess for lymph node involvement in breast cancer.
Explanation: The BRCA1 gene mutation is the most commonly identified genetic alteration associated with hereditary breast and ovarian cancer syndrome. Individuals with BRCA1 mutations have an increased risk of deve
Que
Whi ge
from
1. I
2. A
3. S
4. S
Ans Expl
recei hatic
path mph
node

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